【Offline procurement consulting】

        Phone：15335258233；

        Email：engforlife-mkt@efl-tech.com

【product introduction】

      Methacrylated gelatine (GelMA) has excellent biocompatibility and can be cured under visible light irradiation. It is widely used in cell 3D culture, tissue engineering, bio-3D printing and other research areas. There are tens of thousands of academic papers that have used GelMA hydrogels. In order to improve the efficiency of material exchange between the cells inside the hydrogel and the external environment as well as to provide more space for cell growth and proliferation. The EFL team has successfully developed highly porous GelMA hydrogels (Porous GelMA, EFL-GM-PR series). The EFL-GM-PR series ensures excellent biocompatibility and convenience of operation through a disruptive material science design. Its use is no different from that of conventional GelMA materials, only requiring dissolution and light curing to obtain a hydrogel with a micron pore structure. It not only provides cells with an efficient channel for material exchange, but also provides more space for cell proliferation and growth, significantly increasing the proliferative activity of cells.

【Item】

The photoinitiator LAP mixed well with the material. When preparing 6% w/v gel solutions, the concentration of LAP in the solution is 0.25% w/v.

【Applications】

Cell culture, biological 3D printing, tissue engineering, etc.

【Storages】

Dry kit: room temperature, 3 months; 4℃, 12 months; -20℃, 18 months.

【Operating Procedure】

EFL-GM-PR Series Porous GleMA Hydrogel Operating Procedure 

【Micromorphology】

EFL-GM-PR series porous GleMA hydrogels with controlled microscopic pore structure

【Biological properties】

Cell proliferation inside EFL-GM-PR series porous GleMA hydrogels

EFL-GM-PR series porous GleMA hydrogel surface cell culture (cells in green, fluorescently labelled colloids in red)

【Stability of the incubation process】

      The specific surface area of porous structured hydrogels is much larger than that of normal non-porous hydrogels. As a result, porous hydrogels typically degrade more rapidly than non-porous hydrogels under the same matrix gel strength conditions. The EFL team has optimised the experimental formulation in order to meet the demands of prolonged cell culture. Excellent cell proliferation properties were achieved while maintaining the stability of the porous hydrogels. The EFL-GM-PR series of porous hydrogels showed better performance in terms of cell proliferation and gel stability comparing with regular GelMA non-porous hydrogels.

Digital photos and cell fluorescence photos of the stability test of EFL-GM-PR series porous GleMA hydrogel

【Product Manual】-【EFL-GM-PR series】-Porous Gelatin Methacryloyl