【Offline procurement consulting】

        Phone：15335258233；

        Email：engforlife-mkt@efl-tech.com

【Product introduction】

       Polylysine (ε-PL) is an antibacterial polypeptide (AMP) produced by Streptomyces. It has universal antibacterial activity against both bacteria and fungi, such as Escherichia coli (E.coli) and Staphylococcus aureus (S.aureus). With good biocompatibility, antibacterial and degradable properties, ε-PL and its derivatives are widely used in the field of tissue engineering such as antibacterial wound dressings. It not only promotes tissue repair, but also avoids the disadvantages of traditional antibacterial drugs or metal ions (e.g. Ag+), such as undesirable side effects and poor drug resistance.

       Poly-L-lysine Methacryloyl (PLMA) is a double bond modified poly-lysine which can be cured by UV and visible light in the presence of photoinitiators. The EFL team introduce the PLMA product (EFL-PLMA series) with stable physicochemical properties. It can be cured into gel within 10 seconds under visible light. The material is biocompatible, antimicrobial and offers a wide range of viscoelastic properties to suit different applications.

【Item】

【Applications】

       Antibacterial coatings, wound dressings, etc.

【Storages】

       Dry kit: 4℃, 12 months; -20℃, 18 months.

【HNMR】

Fig 1.Synthesis reaction mechanism and NMR spectrum of EFL-PLMA-001

【Rheological property】

Fig 2. EFL-PLMA-001 rheological properties: (A, B) rheological data of the light curing process;

(C, D) EFL-PLMA-001 viscosity data (honey and water as controls)

【Compression characteristics】

Fig 3. Compression characteristics of EFL-PLMA-001 gels with different concentrations: (A) stress-strain curve; (B) compression strength

【Antibacterial property】

Fig 4. Antibacterial property of EFL-PLMA-001: (A) Schematic diagram of the process of testing the antibacterial property of PLMA by coated plate method; (B/C) Antibacterial effect of PLMA-001 against Escherichia coli and Staphylococcus aureus

【Biocompatibility】 

Fig 5. MC3T3-E1 cells in culture on PLMA composite hydrogel surface (Day1)

Fig 6. Proliferation of MC3T3-E1 on the surface of GM60-5%+PLMA-2% hydrogel group

【3D printing performance】 

Fig 7. PLMA gel structure printed by light-curing bio-3D printer (EFL-BP-86 series)

【Product Manual】-【EFL- PLMA-001】-Poly-L-lysine Methacryloyl